Journal of Oral Tissue Engineering

ORIGINAL ARTICLE
Biocompatibility of Nylon Resin Discs Fabricated by Selective Laser Sintering

Akiko ABE1, Syuichiro KOBAYASHI2, Hironari FUYAMADA1, Daisuke YAMAGUCHI1, Shingo MATSUMURA1, Atsuko UENO1, Yoshinori NAKAMURA3, Kazuo TAKEUCHI1, Hiroshi MURAKAMI1, Tatsushi KAWAI4 and Masami HATTORI1
1Department of Gerodontology,
2Department of Periodontology,
3Department of Removable Prosthodontics,
4Department of Dental Materials Science,
School of Dentistry, Aichi Gakuin University, Nagoya, Japan


J Oral Tissue Engin 2013;11(1):42-50

SYNOPSIS
In bone tissue engineering, scaffolds play a pivotal role for bone regeneration. Recent research has focused on producing scaffolds by 3D modeling for bone tissue engineering. This study evaluates the biocompatibility of selectively la-ser-sintered nylon-12 (SLS Nylon12) as a scaffold material. We perform cytotoxic-ity tests and an implantation test in subcutaneous tissue according to ISO stan-dards. The SLS Nylon12 has good biocompatibility, comparable to the negative control. SLS Nylon12 can therefore be used as a scaffold material for clinical ap-plications.

Key words Laser-sintered nylon-12 (SLS Nylon12), Scaffold, Bone regeneration, Cytotoxicity test, Implantation test