Journal of the Japanese Association of Regenerative Dentistry
J Jpn Assoc Regenerative Dent Vol.7(1) pp.56-63
ISSN 1348-9615


Bond Strength and Bio-Compatibility of Experimental Mineralization Accelerating Adhesives Added Collagen Immobilized Poly Ethylene-co-Vinyl Alcohol (EVA+C)

Yasuo SHINNO1, Mami KISHIMOTO1, Yuka ANABUKI1, Kozo YAMAJI1, Yoshihiro NISHITANI1, Toru TANAKA2, Hidehiko SANO2, Masahiro YOSHIYAMA1
1Department of Operative Dentistry, Field of Study of Biofunctional Recovery and Reconstruction, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
2Department of Restorative Dentistry, Division of Oral Health Science, Graduate School of Dental Medicine, Hokkaido University

The mineralization accelerating adhesion materials that added EVA+C (RMSB) were produced experimentally, and we studied it about a bond strength and the biocompatibility. As a result, bond strength decreased with increase of the EVA+C addition ratio. But the level of the decrease was inhibited when SBP30 was treated. The RMSB group showed a tendency to growth similar to Control at the early phase, and cell count was higher than an SB (Superbond) at high ratio of EVA+C group. It was a combination of SBP30 and 7P (SB/EVA+C = 40wt%/60wt%) that showed a high bond strength and a good cell proliferation. Also, as a result of animal experiment, 7P had weaker inflammation than an SB and mineralized tissue formation was good. It was suggested that it was obtained high adhesive property and biocompatibility by adding EVA+C in an SB at the appropriate ratio in conclusion.

Keyword: Dentin regeneration, Pulp capping, Adhesive